Actress Drew Barrymore is opening up about one of the most turbulent childhoods in Hollywood — and why, despite years of personal struggles, she says she has no regrets about the path that shaped her.

During a candid appearance on comedian Bill Maher’s podcast, Club Random, the longtime actress reflected on growing up in the spotlight and navigating fame at an age when most children are still figuring out middle school.

Barrymore, who became a household name as a child star, has spoken publicly for years about the difficult experiences that marked her early life. In the conversation, she revisited the chaos of her youth, including her battles with addiction at just 12 years old and the emotional turmoil that followed shortly after.

The Never Been Kissed star previously detailed many of those struggles in her memoir Little Girl Lost, released in 1990. By the time she was a young teenager, Barrymore had already entered rehab and later spent more than a year in a treatment facility after being labeled mentally ill. She also endured a deeply painful period that included a suicide attempt at 14.

Yet despite the hardships, Barrymore surprised listeners with her outlook on the experience.

Rather than expressing bitterness, the actress said she embraces her past and believes it ultimately helped shape the person she became. Looking back, she described her unconventional upbringing with a sense of acceptance, even humor at times.

That perspective has changed, however, now that she’s raising children of her own.

Barrymore, who is the mother of two daughters, admitted that parenthood gave her a completely different understanding of boundaries and protection. She joked that becoming a mom has made her realize just how shocking parts of her childhood truly were.

The actress also used the interview to discuss her approach as host of The Drew Barrymore Show, explaining why she tries to create a more personal atmosphere for guests rather than relying on a rigid interview format.

According to Barrymore, years of sitting across from reporters taught her what she didn’t want her own conversations to feel like. She recalled experiences with interviewers who appeared more focused on the next prepared question than on genuinely listening.

That disconnect, she explained, motivated her to build something different on her daytime talk show — a style centered more on authentic discussion than scripted exchanges.

Barrymore said she values natural conversation over traditional question-and-answer sessions, emphasizing connection and emotional openness with the people who appear on her program.